An effective vaccine prioritization process is essential to prevent the many issues that currently weaken global vaccination efforts. Identifying challenges associated with vaccine development is important when considering which initiatives will provide immunization that is effective, affordable, and easy to administer. The process of establishing priorities for vaccine development is complicated, though, by the conflicting interests of multiple stakeholders involved in the vaccine market. Additionally, uncertainties exist regarding: (1) the resources and time required for vaccine development, (2) the expected benefits of development, and (3) the anticipated demand for vaccination, further complicating the prioritization process. This study proposes a decision-support tool for prioritizing vaccine initiatives through the use of mathematical optimization models. The tool allows a panel of decision makers to assess vaccine candidates over multiple criteria with information that is both quantitative and qualitative. This assessment is the result of a methodology that integrates Data Envelopment Analysis and the Analytic Hierarchy Process. The decision-support tool could be used by researchers and funding agencies to determine which vaccine initiatives should be: more effective, affordable, profitable, reliable, easier to use and store, and more suitable to the needs of multiple populations from diverse locations and having multiple logistic needs.
Library of Congress Subject Headings
Vaccination--Developing countries--Planning--Mathematical models; Multiple criteria decision making; Data envelopment analysis
Department, Program, or Center
Industrial and Systems Engineering (KGCOE)
Schmoke, Timothy, "An Optimization-based approach for vaccine prioritization" (2013). Thesis. Rochester Institute of Technology. Accessed from
RIT – Main Campus