A general protocol for conversion of a tetrasubstituted alkene to a highly methylated hydrocarbon is tested with a concise synthesis of the natural product, herbertene. The conversion: alkene --> 1,2-diol --> 1,2-dimethylated hydrocarbon should find application in a number of synthesis designs.
Department, Program, or Center
School of Chemistry and Materials Science (COS)
Synthesis 1998N6 (1998) 832-834
RIT – Main Campus