Biomedical Engineering research utilizes digital three-dimensional models of human anatomical systems that are used as components in specific types of simulation. The data collected from the simulations provide quantifiable information that has a physical basis. The use of the digital models allows engineers the freedom of experimentation that may not be possible in the real world and allows them to quickly change the parameters. Although these models can provide reliable information, the models represent a mechanical ideal and therefore do not accurately represent organic matter. The consequence of using an ideal model to represent tissue may give flawed data, since the mechanical simulation does not identically represent living tissue. The purpose of this thesis was to develop the methodology and actual creation of a three-dimensional model that was a physically accurate representation of organic lung acinar tissue. The objective is to have the model input into analytical software that will calculate the flow dynamics of the organic tissue represented by the model. Specifically, the model represents alveolar ducts in lung tissue. The model starts from the transitional bronchioles through the alveolar ducts and ends at the terminal alveolar sacs. Creating this model was challenging due to the microscopic size and inherent density of the tissue, making it difficult to determine structure.
Library of Congress Subject Headings
Computer simulation; Computer animation; Lungs--Models; Lungs--Foreign bodies--Computer simulation; Fluid dynamic measurements
Weisman, Jessica L., "Using Organic Modeling Techniques to Create Scientific Models for Flow Analysis in Biomechanical Research: Exploring 3-D software typically used in creative media for model creation." (2007). Thesis. Rochester Institute of Technology. Accessed from
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