The use of cell based biosensors outside of the laboratory has been limited due to many issues including preparation of the sample, maintenance of the biological environment, incorporation of the appropriate sensors, and integration of the electronics for data collection and analysis. This paper describes these system issues and briefly presents current efforts to address packaging, fluidics, and data interpretation. These include the development of an integrated silicon-PDMS cell cartridge system that provides reliable electrical and fluidic interconnect and a regulated cell environment, the development of low power and low overhead sensors and electronics, and the necessary fluidic sample preparation.

Date of creation, presentation, or exhibit



Micro Total Analysis Systems (MuTAS) Workshop (1998) 443-446 The original publication is available at DeBusschere is partially supported by a NDSEG Fellowship and project funding was provided by the DARPA MicroFlumes Program (Contract Number: N66001-96-C-8631).Note: imported from RIT’s Digital Media Library running on DSpace to RIT Scholar Works in February 2014.

Document Type

Conference Proceeding

Department, Program, or Center

Microsystems Engineering (KGCOE)


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