From the Journal of Medical and Biological Engineering and Computing The original publication is available at www.springerlink.com Pulse compression techniques that are capable of producing a large signal-to-noise (SNR) enhancement, have been used successfully in many different fields. For medical applications, frequency-dependent attenuation in soft tissue can limit the usefulness of this method. In the paper, this issue is examined through model-simulation studies. Frequency-modulation (FM) chirp, considered in the study, is just one form of pulse coding technique. Pulse propagation effects in soft tissue are modeled as a linear zero phase filter. A method to perform simulations and estimate the effective time-bandwidth product K is outlined. K describes the SNR enhancement attainable under limitations imposed by the soft-tissue medium. An effective time-bandwidth product is evaluated as a function of soft-tissue linear attenuation coefficient αo, scatterer depth z and the bandwidth of the interrogating FM pulse, under realistic conditions. Results indicate that, under certain conditions, K can be significantly lower than its expected value in a non-attenuating medium. It is argued that although limitations exist, pulse compression techniques can still be used to improve resolution or increase penetrational depth. The real advantage over conventional short-pulse imaging comes from the possibility that these improvements can be accomplished without increasing the peak intensity of the interrogating pulse above any threshold levels set by possible bio-effect considerations.
Department, Program, or Center
Chester F. Carlson Center for Imaging Science (COS)
Rao, Navalgund, "Investigation of a pulse compression technique for medical ultrasound: A Simulation study" (1994). Journal of Medical & Biological Engineering & Computing, Vol. 32 (),Accessed from
RIT – Main Campus