Heme was a noncompetitive inhibitor (apparent Ki and K'i = 0.043 mM) of a ferrisiderophore reductase purified from Bacillus subtilis; protoporphyrin IX had no effect. The cellular level of heme may partly regulate the function of this reductase to yield a controlled flow of iron into metabolism.
Department, Program, or Center
Thomas H. Gosnell School of Life Sciences (COS)
Journal of Bacteriology 152N2 (1982) 943-945
RIT – Main Campus