The developmental course of activity changes of 4 endogenous membrane glycosyltransferases: UDP-glucose : glycosyltrasferase, UDP-galactose : glycosyltransferase, GDP-mannose: glycosyltransferase, and UD-PN-acetylglucosamine : glycosyltransferase was determined in various stages of developing sea-urchin embryos from unfertilized eggs up to the 16-cell stage. The results show that there is a 2-fold increase in glycosyltransferase activity after fertilization. These results are discussed in relation to the postulated role of glycosyltransferases in mediating adhesion, recognition, and agglutination of cells and embryos.

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Article may be found at: http://jcs.biologists.org/cgi/reprint/25/1/355 This work was supported in part by grants GM15190 and CA 13320. H.B.B. is a Scholar of the Leukemia Society of America.ISSN:1477-9137 Note: imported from RIT’s Digital Media Library running on DSpace to RIT Scholar Works in February 2014.

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Department, Program, or Center

Thomas H. Gosnell School of Life Sciences (COS)


RIT – Main Campus