Abstract
A general protocol for conversion of a tetrasubstituted alkene to a highly methylated hydrocarbon is tested with a concise synthesis of the natural product, herbertene. The conversion: alkene --> 1,2-diol --> 1,2-dimethylated hydrocarbon should find application in a number of synthesis designs.
Publication Date
1998
Document Type
Article
Department, Program, or Center
School of Chemistry and Materials Science (COS)
Recommended Citation
Synthesis 1998N6 (1998) 832-834
Campus
RIT – Main Campus
COinS
Comments
This article may be accessed on one of the author's websites at: http://ochem.jsd.claremont.edu/pubs.dir/Synth_1998_p832(Poon).pdf Support by way of a Bristol–Myers Squibb Award of Research Corporation is gratefully acknowledged. T. Poon and B. P. Mundy thank the Camille and Henry Dreyfus Foundation for their generous support. Paul Schupf and the National Science Foundation are acknowledged for their support of the Colby Chemistry Computational Facilities. HRMS data were supplied by Dr. Joe Sears, Montana State University Mass Spectrometry Facility, Bozeman, MT.ISSN:1437-210x Note: imported from RIT’s Digital Media Library running on DSpace to RIT Scholar Works in February 2014.